
What is the design used by Graham et al?
Input parameter Design choice
Target cohort (T) dabigatran new users with prior atrial
fibrillation
Comparator cohort (C) warfarin new users with prior atrial
fibrillation
Outcome cohort (O) Ischemic stroke
Time-at-risk
1 day after cohort start ïƒ cohort end
Model specification 1:1 propensity score-matched univariable
conditional Cox proportional hazards